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OviVance contains a unique blend of plant-derived phytochemical ingredients, vitamins and minerals that combats PCOS and its symptoms, optimises reproductive health and combat insulin resistance related to common gynaecological and metabolic disorders. This blend leads to more rapid improvement in insulin sensitivity and hormonal imbalances.
Hormonal disorders can cause:
• Irregular and painful periods
• Abnormal hair growth
• Trouble falling pregnant
• Weight gain
• Menopausal symptoms
Take 2 tablets per day with meals. You can break or chew the tablets if you need.
The ingredients contained in OviVance generally have low side-effect profiles even when used for extended periods. Side-effects are unlikely to be experienced at the dosages provided by OviVance. For large doses of the individual ingredients, side-effects are mostly of a gastrointestinal nature, including abdominal discomfort or nausea. To reduce the chance of side effects, it is recommended that OviVance is taken with meals.
OviVance has a NAPPI code, which means that most medical aids will pay for it, as long as you have a medical aid savings option with available savings.
While inositol is included in OviVance specifically to aid in insulin and hormonal balance in PCOS and MetS, it is an extremely safe molecule, and will have no ill-effects if you do not suffer from any of the above conditions. In fact, inositol has been shown to have some benefits when taken by healthy people. The remainder of the ingredients are all vitamins and minerals that, while beneficial to persons with metabolic conditions, are also essential to health in pregnancy and general well-being.
PCOS is a condition that results from an imbalance in reproductive hormones, which leads to irregular ovulation, disrupted metabolism and cosmetic issues. Symptoms sometimes start around puberty, especially if hormonal imbalance is the main cause, but can also develop later, often in response to weight gain and insulin resistance.
Importantly, PCOS is not a clear-cut disorder, each person can experience varying degrees of the symptoms below- some may have just one or two while others have many.
The main symptoms of PCOS include, and can be varying combinations of:
Independent research has shown that the ingredients contained within the unique blend of plant derived (phytochemical) ingredients, vitamins and minerals in OviVance leads to more rapid improvement in insulin sensitivity and hormonal imbalances. OviVance optimises women’s health and gynaecological functions.
Each person’s reaction to treatment is different, and depends on your level of Insulin Resistance. Insulin Resistance is a progressive disease that increases in severity over time, with increasing effects on your body. Most people taking OviVance have seen positive changes within a few weeks to a few months.
Remember, if Insulin Resistance (the underlying cause) is left untreated the symptoms will return or even increase as Insulin Resistance increases. If properly treated, however, the conditions and effects
are reversible.
OviVance can benefit you in many ways, and can be used for:
Yes, OviVance is specifically designed to optimise reproductive health and ovarian function, by combatting insulin resistance related to common reproductive disorders like Polycystic Ovarian Sydrome (PCOS). The specific ratio of the Inoline-F blend of ingredients in OviVance has a more rapid response in insulin sensitivity and hormonal imbalances, thereby minimising the symptoms of PCOS including central obesity (excess weight around your waist), irregular menstrual cycles, infertility, acne, excessive hair growth, hormonal hair loss and hyperpigmentation.
OviVance is a unique blend of scientific-natural ingredients, proven to optimise reproductive health and healthy ovarian function, making it perfect for female health. All the ingredients in OviVance are safe for everyday use and enhance health whether you suffer from PCOS or not. OviVance will have no negative effects on your body if you do not suffer from PCOS. The scientifically proven ingredients are beneficial for general health and well-being in women.
Yes, OviVance is safe to use in conjunction with other fertility treatments, and can result in improved chances of conceiving, though we recommend that you take the OviVance package insert to your treating doctor or fertility specialist for their advice.
No, OviVance will not interfere with the actions of oral contraceptives. In fact, the scientific-natural blend of ingredients in OviVance can be used in combination with your pill or other contraception to better regulate your menstrual cycle, not to mention the other female health benefits you’ll get.
OviVance is an all-in-one product for mom and baby, and contains all the essential vitamins needed when you are pregnant to optimise the health and development of your baby in the womb.
Remember, your doctor should always know on what medication you are on, both before and during pregnancy.
You do not need to take in extra folic acid if you are using OviVance it is an all in one product. The Folate in OviVance is the natural form of folic acid (synthetic form), which means that, with folate, your bioavailability is better through rapid absorption, making it safer to use too.
Yes. Hormonal imbalances negatively influence oocyte development and ovulation, which leads to irregular menstruation, ovary disfunction and infertility. The specific ratio of the unique Inoline-F blend of scientific-natural active ingredients in OviVance leads to rapid improvement in insulin sensitivity and hormonal imbalances, resulting in improved menstrual function and regulation.
Each person’s reaction to treatment is different, and depends on your level of Insulin Resistance. Insulin Resistance is a progressive disease that increases in severity over time, with increasing effects on your body. Most people taking OviVance have seen positive changes within a few weeks to a few months.
Remember, if Insulin Resistance (the underlying cause) is left untreated the symptoms will return or even increase as insulin resistance increases. If properly treated, however, the conditions and effects
are reversible.
Every person reacts differently to treatment, which depends on your level of Insulin Resistance and the severity of your Polycystic Ovarian Syndrome (PCOS). The good news is that both the condition and the symptoms respond well to treatment.
The specific scientific ratio of the unique Inoline-F blend used in OviVance causes a rapid improvement in insulin sensitivity and hormonal balances, and has shown to have an effect in you already, i.e. spotting/bleeding is not uncommon and is actually a good sign that the product is starting to work.
Because OviVance treats an underlying condition and not just the symptoms, it may take up to 1-3 months to stabilise your hormones and regulate your periods.
No, the unique Inoline-F blend of scientific-natural ingredients in OviVance may act to improve irregular cycles and fertility. Also, taking OviVance will not interfere with the actions of oral contraceptives, induce excessive menstruation, or have other ill effects if you have no goals of having a child. It is safe for everyday use and is designed to enhance overall female health.
Yes. An imbalance of hormones in the uterus creates and optimal environment for fibroids to develop. OviVance contains the unique Inoline-F blend of scientific-natural ingredients that leads to rapid improvement in insulin sensitivity and hormonal imbalances, and can help re-establish healthy hormone balances in the uterus.
Yes, the specific ratio of the Inoline-f blend in OviVance leads to rapid improvement in hormonal imbalances and optimises reproductive health and ovarian function. However, we recommend that you see your gynecologist immediately if you suspect that you have cysts.
You are more likely to develop a follicular cyst if you:
Blocked tubes are caused by scar tissue due to operations or infections and therefore cannot be helped by OviVance.
OviVance is indicated for:
OviVance is not indicated for endometriosis, but can help with:
PCOS and its symptoms:
Enhancement of fertility
Combatting gestational diabetes
Improving blood sugar control when pregnant
Pre-and-Post – menopausal
Metabolic Syndrome
Optimise women’s health and gynaecological functions
If you have primary ovarian insufficiency, we recommend you speak to your treating doctor to understand what your options may be to start or expand your family. The unique Inoline-F blend of scientific-natural ingredients in OviVance can promote reproductive health, making it a great choice for combination therapy.
Yes. There is a mutual inter-relationship between menopause and Insulin Resistance. Age, hormonal changes and abdominal weight gain affect how cells respond to insulin and is predictive of Insulin Resistance in menopausal women. Insulin Resistance is also a primary mediator of the Metabolic Syndrome and many studies have shown an increased risk of Metabolic Syndrome in menopausal women.
OviVance contains the Inoline-F blend of scientific-natural active ingredients. This specific ratio leads to rapid improvement in insulin sensitivity and hormonal imbalances. OviVance also contains a blend of vitamins and minerals that were carefully selected based on the scientifically- proven results it has on women’s health.
Independent research has shown that the ingredients contained within OviVance combat Insulin Resistance related to common gynaecological reproductive and metabolic disorders like Polycystic Ovarian Syndrome (PCOS) and Metabolic Syndrome (MetS.)
Yes. There is a mutual inter-relationship between menopause, its symptoms and insulin resistance. OviVance combats Insulin Resistance, a condition common in menopausal women that puts you at a greater risk for developing the Metabolic Syndrome.
For optimal results, it is better to take both tablets once with a meal.
Today! You can start taking OviVance any day of your cycle.
For PCOS:
As a daily supplement:
There is no cure for PCOS, but the good news is that the condition and the symptoms respond well to treatment. OviVance targets an underlying cause of the condition, thereby managing Polycystic Ovarian Syndrome (PCOS) with great success. We recommend OviVance as our first choice in combatting PCOS.
For Pregnancy:
From planning a pregnancy until the birth of your baby.
A great advantage of OviVance is that it is not only formulated for use before, but also during pregnancy, optimising foetal health and development. OviVance is an all-in-one product for mom and baby.
For Menopause and combatting the Metabolic Syndrome:
As a daily supplement.
For General female health:
As a daily supplement.
Thyroid disorders are a special precaution not a contraindication, therefore OviVance may be used in combination with Thyroid medication with caution. We recommend you take the package insert to discuss with your treating doctor.
Usually, ovulation occurs 2 weeks before your period starts; this is the most fertile time in a woman’s cycle. So, if you take the number of days in your usual cycle and subtract 14, you’ll be able to determine the best time to try and conceive. For example, a woman with a 32-day cycle would likely ovulate around day 18 (32-14=18), while a woman with a 28-day cycle would ovulate around day 14 (28-14=14). Intercourse should take place regularly on the days before, on the day and a few days after for the best chance of falling pregnant.
A regular period is the best indication that you’re ovulating. Count the first day that you have a full flow of blood, to the next time and day you have a full flow this will tell you how many days are in your menstrual cycle. Usually, having a cycle that is between 24-36 days is considered regular. Keeping track of your menstrual cycle is a valuable part of your medical history, should you need to see a fertility specialist.
Increased cortisol level due to chronic stress can have a negative effect on your reproductive health. Trying to conceive can contribute to extra stress on a couple’s relationship and should not be ignored. NeuroVance can combats stress and anxiety and can be used in combination with OviVance and other medication.
OviVance contains a unique blend of plant-derived phytochemical ingredients, vitamins and minerals that targets PCOS and its symptoms, optimises reproductive health and combat insulin resistance related to common gynaecological and metabolic disorders. This blend leads to more rapid improvement in insulin sensitivity and hormonal imbalances.
Hormonal disorders can cause:
OviVance combats insulin resistance related common gynaecological disorders. It contains a unique blend of plant- derived phytochemical ingredients, vitamins and minerals that help to optimise your reproductive health and ovary function before and during pregnancy. It also assists you in combatting insulin resistance related to common reproductive disorders, such as Polycystic Ovary Syndrome (or PCOS).
OviVance can be used for:
OviVance combats insulin resistance related to common gynaecological disorders. It contains a unique blend of plant-derived phytochemical ingredients, vitamins and minerals that help to optimise reproductive health. This blend leads to more rapid improvement in insulin sensitivity and hormonal imbalances.
These ingredients are:
Inositol, a naturally occurring nutrient which exist in the body in two forms: myo (MI) and D-chiro-inositol (DCI). Both act in fertility, reproduction and metabolic health. Problems in the balance between these two forms of inositol results in reduced insulin sensitivity and poor ovary function. Clinical studies have shown that inositol, especially at the ratio provided by OviVance, improves regulation of insulin and insulin sensitivity, ovulation and follicular maturation, egg quality and quantity and restores menstrual cycle regularity.
OviVance contains L-5-methyltetrahydrofolate (5-MTHF), the natural form of folate, offering benefits such as better absorption and increased safety. Folate is essential to reproductive and foetal development, and supplementation improves menstrual function and regularity of ovulation, enhances reproductive outcomes and response to fertility treatment, and helps prevent neural tube defects, preeclampsia, miscarriage and congenital abnormalities. Regarding MetS and PCOS, folate aids in avoiding hyperhomocysteinemia, a condition responsible for cardiovascular damage and cancer.
Choline is a vital nutrient in liver, neurological, musculoskeletal and cellular membrane function. During reproduction and pregnancy, choline is essential due to increased cell-division and membrane synthesis, reduces placental inflammation, improves placental vascular development and angiogenesis, and leads to better neurodevelopment and further reduced chance of neural tube defects.
Vitamin A is a nutrient essential to normal growth, especially during foetal, neonatal and childhood development of the organs and immune system.
Vitamin B6, a coenzyme in over one hundred enzymatic reactions is known to reduce the symptoms of morning sickness, nausea, vomiting and postpartum depression. The vitamin is also involved in reducing homocysteine, benefitting PCOS patients.
Vitamin B12 is essential to optimal infant neurological development and prevention of neural tube defects, pre-term delivery and preeclampsia amongst others. The vitamin is also involved in reducing homocysteine levels alongside folate, vitamin B6 and choline.
Vitamin D positively affects the ability to conceive through improved egg maturation, fertilisation rates and menstrual regularity, and reduces risk for preterm birth and preeclampsia. The vitamin is also well known to assist in MetS and PCOS through reduction in insulin resistance, dyslipidaemia and obesity.
Iodine is required for synthesis of thyroid hormones, and low intake reduces fertility rates, impairs neurodevelopment, and leads to spontaneous miscarriage, congenital abnormalities and other issues in pregnancy.
Magnesium improves pregnancy rates and reduces the occurrence of preterm labour, preeclampsia and growth restriction. It also assists metabolic aspects of female health, especially in terms of MetS, PCOS and reducing the risk of gestational diabetes.
Selenium occupies major roles in immunity and redox processes. Supplementation may lessen the risk of neural tube defects and preeclampsia, while improving cognitive development. It also has well established roles in MetS and PCOS, insulin sensitization, inverse relationship with androgenic hormone levels
Zinc is important to optimal health during pregnancy, as well as addressing PCOS and MetS, especially through reducing inflammation and oxidative stress, improving insulin sensitivity, blood sugar regulation and dyslipidaemia.
One tablet contains:
| Ingredients | |
| Inoline-F Inositol (myo:D-chiro inositol 40:1) Folate (as L-5-methylhydrofolate calcium) Choline (as choline bitartrate) | 1000 mg 200 mcg 25 mg |
| Vitamins Vitamin A (beta-carotene) Vitamin B6 (pyridoxine HCL) Vitamin B12 (cyanocobalamin) Vitamin D3 | 83 mcg RE 1 mg 3 mcg 200 IU |
| Minerals Iodine (as potassium iodide) Magnesium (as magnesium oxide) Selenium (yeast) Zinc (as zinc oxide) | 75 mcg 75 mg 15 mcg 7.5 mg |
OviVance is ideal for women experiencing any of the symptoms related to PCOS, including metabolic syndrome (MetS) and gestational diabetes. OviVance is effective in assisting with the management of metabolic changes associated with menopause, especially if it taken on a long term basis. OviVance combats insulin resistance related to common gynaecological disorders.
Take 2 tablets per day with meals. You can break or chew the tablets if you need.
You should not take OviVance if you are hypersensitive or allergic to any of the active or inactive ingredients of OviVance. Using any supplements or medications while pregnant should be according to the advice of your doctor.
The ingredients contained in OviVance generally have low side-effect profiles even when used for extended periods. Side-effects are unlikely to be experienced at the dosages provided by OviVance. For large doses of the individual ingredients, side-effects are mostly of a gastrointestinal nature, including abdominal discomfort or nausea. To reduce the chance of side effects, it is recommended that OviVance is taken with meals.
Yes, OviVance may be taken with most prescription drugs, including oral contraceptives and diabetic drugs such as metformin. Caution, however, must be taken with anti-diabetic medication, as the blood sugar-lowering effect of OviVance may enhance their action and leave you with symptoms of low blood sugar. Caution must also be taken when used with blood thinners such warfarin. It is always important to inform your doctor of what supplements you are taking, especially if you are already being treated for another condition.
Inositol
Inositol is a naturally occurring vitamin B-like nutrient. Of nine stereoisomers, myo-inositol (MI) and D-chiro-inositol (DCI) are the most abundant in tissues.
MI and DCI act in fertility related hormone signalling, reproduction and metabolic health, including insulin, gonadotropin, thyroid, and anti-Müllerian hormone signalling pathways. Each isomer has varying roles as second messengers and exhibit tissue specific ratios. In polycystic ovary syndrome (PCOS) and metabolic syndrome (MetS), dysregulation of inositol metabolism and homeostasis has been associated with a number of health outcomes, including reduced insulin sensitivity, dyslipidaemia and aberrant function of the ovaries.
In clinical settings, supplementation of inositol has been demonstrated to offer a number of benefits. These include improvement in the optimal regulation of insulin, insulin sensitivity, glycaemic and lipid levels, blood pressure control and a reduction in the prevalence and severity of gestational diabetes. Reproductive health is also positively affected, which may in part be due to improved endocrine function and reduced hyperandrogenism through increased frequency of ovulation and follicular maturation, improved oocyte quality and quantity and restoration of spontaneous ovulation and menstrual cycle regularity.
In many of these outcomes, combined treatment with MI and DCI at the physiologically relevant ratio of 40:1 has been shown to lead to more rapid improvement, resulting in the international consensus that supplementation at this ratio is optimal in treatment of a range of metabolic and reproductive abnormalities.
Folate
Folate, also known as Vitamin B9, is involved in numerous aspects of cellular function and general health. Folates cannot be synthesized by the body, and as such must be obtained from the diet. Due to the wide ranging roles of folate in metabolism, deficiency can have substantial effects on health, especially relating to foetal health during early pregnancy.
Adequate levels of folate are essential to reproductive and foetal development. Positive reproductive effects involve improved menstrual function and regularity of ovulation, partially attributed to better luteal phase progesterone measurements. Indeed, folate supplementation has been associated with enhanced reproductive outcomes and response to fertility treatment. In pregnancy, folate sufficiency is well known to prevent the development of neural tube defects in the foetus, but has also been demonstrated to be negatively associated with preeclampsia, miscarriage and congenital abnormalities such as heart defects and oral facial clefts. Furthermore, folate is essential for angiogenesis and vasculogenesis leading to adequate foeto-placental circulation and may be involved in neurodevelopment of children.
Folate may also benefit women suffering from MetS and PCOS through its role in prevention of hyperhomocysteinemia, a condition responsible for cardiovascular damage and cancer, through its role in regulating homocysteine.
OviVance contains L-5-methyltetrahydrofolate (5-MTHF), the natural form of folate, as opposed to folic acid, a synthetic form that is most often found in fortified foods and supplements. Despite the widespread success of folic acid supplementation in improving health, it is believed that the natural form offers a number of benefits, such as better bioavailability through more rapid absorption.
Choline
Choline is a vital nutrient in optimal liver, neurological, musculoskeletal and cellular membrane function. The majority is obtained from animal derived foods. Vegetarians and vegans are therefore especially susceptible to choline deficiency, while the majority of pregnant and lactating women, and a large proportion of the general population, exhibit some level of choline insufficiency.
Choline deficiency can lead to a number of pathologies, including fatty liver disease, muscle damage, decreased cognitive function, cancer and homocysteinaemia. During reproduction and pregnancy, choline is essential to increased cell-division and membrane synthesis. Supplementation reduces placental inflammation, improves placental vascular development and angiogenesis, and leads to better neurodevelopment and further reduced chance of neural tube defects.
Vitamin A
Vitamin A is a nutrient essential to normal growth, especially during foetal, neonatal and childhood development. The vitamin is well-known to be crucial for ocular integrity and development, but also has roles in development of the foetal organs and skeleton, immune system, teeth, hair, skin and mucous membranes as well as the functional capacity of reproductive organs.
Vitamin B6
As a coenzyme in over one hundred enzymatic reactions, vitamin B6 is an important nutrient in human health. The vitamin is available in many food sources of both plant and animal origin, and supplementation in the general population is believed to lead to a number of positive outcomes.
In pregnancy, the major role of Vitamin B6 supplementation has been to reduce the symptoms of morning sickness, nausea, vomiting and postpartum depression. Vitamin B6 is also involved in reducing homocysteine levels along with folate, and thus may benefit PCOS patients.
Vitamin B12
Vitamin B12 fulfils dominant roles in the synthesis and methylation of DNA and energy metabolism. It can only be obtained from animal derived foods, and supplementation is therefore especially important in vegetarians and vegans.
In relation to pregnancy and reproductive health, vitamin B12 deficiency is associated with increased risk of adverse neonatal and maternal outcomes, including pre-term delivery, low birth weight and preeclampsia. Vitamin B12 is also essential to optimal infant neurological development and prevention of neural tube defects, and increased intake is often required due to enhanced supply to the child in both pregnancy and lactation.
With regards to PCOS and MetS, vitamin B12 is involved reducing homocysteine levels, and as such may aid in preventing hyperhomocysteinaemia in women suffering from the condition. Vitamin B12 supplementation is also essential alongside that of folate, as insufficiency in conjunction with high folate levels increases risk of gestational diabetes and maternal obesity.
Vitamin D
The vitamin D’s are a group of fat-soluble steroid vitamins. Vitamin D has wide ranging effects on general health, from participating in immune function to cardiovascular and skeletal viability.
In terms of reproductive health, Vitamin D positively affects the ability to conceive through improved oocyte maturation, as well as reduces the risk for preterm birth and preeclampsia. Additionally, the vitamin is linked to placental function and skeletal and lung development in utero.
MetS and PCOS related outcomes are also affected by vitamin D status and supplementation. These include improved metabolic parameters, as well as a reduction in insulin resistance, dyslipidaemia and obesity. Higher vitamin D availability has similarly been shown to improve fertility and fertilisation rates as well as menstrual regularity among obese women with or without PCOS.
Iodine
Iodine is primarily required for synthesis of thyroid hormones, especially in pregnant women where iodine requirements are increased. Iodine is essential to the health of both mother and foetus, and low intake has been implicated in reduced fertility rates, sub-optimal neurodevelopment, spontaneous miscarriage, congenital abnormalities and decreased mental acuity later in life.
Magnesium
Magnesium is a trace element involved in more than 300 enzymatic reactions. Suboptimal magnesium levels or deficiency is associated with a number of disorders and requirement for the mineral increases during gestation.
Magnesium sufficiency has been linked to improved pregnancy rates and a reduction in the occurrence of preterm labour, preeclampsia, small for gestational age foetuses and growth restriction. The mineral is also associated with improving metabolic aspects of female health, especially in terms of MetS associated with PCOS and reduction in the chance of gestational diabetes.
Selenium
Selenium, another trace element, plays a major role in facilitating immunity and redox processes.
In pregnancy, deficiency can lead to various adverse outcomes, including increased risk of neural tube defects and impaired cognitive development. Supplementation has also been observed to reduce the risk of preeclampsia. Additionally, selenium plays a role in MetS and PCOS, exhibiting insulin sensitization properties, an inverse relationship with androgenic hormone levels, and an ability to attenuate dyslipidaemia.
Zinc
Zinc is an essential mineral required for normal health and acts as a cofactor in hundreds of enzymatic reactions.
Zinc deficiency in pregnancy is associated with various adverse outcomes, including spontaneous miscarriage, congenital malformations, intrauterine growth retardation, labour abnormalities and preterm delivery. Metabolic effects of zinc have also been observed to benefit PCOS and MetS through reducing inflammation and oxidative stress, improving insulin sensitivity and glycaemic parameters, and attenuating dyslipidaemia. Zinc supplementation in women with PCOS has demonstrated a reduction in the risk of gestational diabetes, hirsutism and androgenic alopecia.
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