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AntaGolin contains a blend of plant-derived phytochemical ingredients that combats insulin resistance and optimises blood-sugar metabolism. This unique combination supports multiple pathways involved in the input, output and processing of sugars in the body and the optimal regulation of metabolism.
Poorly managed blood sugar metabolism can be associated with insulin resistance, a condition that makes it difficult to lose weight. If Insulin resistance is not identified and managed appropriately it can lead to numerous conditions.
These include:
• Increase in weight gain
• The metabolic syndrome
• Abnormal cholesterol
• Poor cardiovascular health
• Diabetes
• Liver disease
Trials conducted in South Africa as well as the USA, evaluated by independent medical experts, have indicated that taking AntaGolin in conjunction with lifestyle modification makes you lose more weight than lifestyle modification alone. AntaGolin can also be used by individuals with glucose intolerance or pre-diabetes, type 2 diabetes, or insulin resistance related to polycystic ovarian syndrome (PCOS). AntaGolin is an ideal product to use with any weight-loss or weight-maintenance programme.
ADULTS: Starting dose:
Take 1 AntaGolin three times a day, with meals
Maintenance Dose:
Take 1 AntaGolin twice a day with meals
AntaGolin generally has a low side-effect profile even when used for extended periods. Gastrointestinal side effects, including abdominal fullness and nausea have been reported. Individuals on diabetic medication may develop low blood sugar, especially if AntaGolin is taken on an empty stomach. It is therefore recommended that AntaGolin is taken with meals.
To test the efficacy of AntaGolin in clinical practice, the Medical Nutritional Institute conducted a series of 11 in-house observational studies on obese and overweight individuals, initially in South Africa and later in the USA as well. In all the studies, subjects taking AntaGolin in combination with lifestyle intervention lost, on average, twice the amount of weight as compared to a control group on lifestyle intervention alone. All studies also demonstrated a significant statistical decrease in the total amount of abdominal fat after treatment with AntaGolin, as measured by a reduction in waist circumference.
Yes, AntaGolin can be used in combination with Glucophage/Metformin. Our experience has shown an improved outcome of individuals who use such a combination. Please do not discontinue the use of your chronic prescription medication without the consent of your doctor. We advise against replacing Glucophage/Metformin with AntaGolin. For individuals who are not on Glucophage/Metformin, AntaGolin can be taken on its own to combat insulin resistance.
During these occasions, AntaGolin can be used as a form of damage control for weight maintenance. AntaGolin may stabilise blood sugar, blood fat and blood insulin levels, thereby preventing the vicious cycle of fat formation and fat preservation from recurring. AntaGolin is an ideal product to use with any weight-loss or weight-maintenance programme.
Yes, AntaGolin may assist you with your appetite control. Consistently high blood glucose levels, in the presence of insulin resistance, leads to cells that are starved of glucose. Since these cells are in need of energy, they send hunger signals to the brain via a biochemical signalling mechanism. This leads to increased eating and the intake of excess glucose that is eventually stored in the body as fat.
AntaGolin should be taken within 30 minutes after a meal. As far as possible, we recommend that AntaGolin be taken with meals for optimal blood sugar control and the prevention of a glucose-insulin peak.
Yes, AntaGolin safe and effective for weight loss. Recently, two independent medical experts evaluated AntaGolin, a product designed to help reduce body fat by combatting insulin resistance through a unique mode of action. Both experts concluded that the claim “AntaGolin is safe and effective” is not only scientifically sound but also clinically demonstrable as well.
According to the World Health Organisation (WHO), a waist circumference of more than 80 cm in females, and more than 94 cm in males, is an indication that you may be suffering from insulin resistance.
Metabolic Syndrome is the collective term used for a group of interlinked medical conditions that all pose a significant health risk. If left unchecked, the cumulative effect of these conditions statistically reduces life expectancy by increasing the risk for developing heart disease, high blood pressure and diabetes, as well as various forms of cancer. Although genetic factors play a role, the underlying cause that leads to the development of Metabolic Syndrome relates to the progressive accumulation of excess body fat.
AntaGolin works via multiple pathways to combat insulin resistance, helping you to maintain your weight. The correct dosage for weight maintenance is 1 tablet 2 times per day with meals. AntaGolin is particularly helpful in this regard during holidays, festive seasons and other celebrations when you do not have control over the food that is served or the way the food is prepared.
No, it will not. The mechanisms of action are different for AntaGolin compared to contraceptive methods and medications, so the risk for possible drug interactions should be minimal.
For Namibian clients, AntaGolin is now also available at pharmacies without a prescription.
Recently, two independent medical experts evaluated AntaGolin, a product designed to help reduce body fat by combatting insulin resistance. Based on its unique mode of action, in all the studies, subjects taking AntaGolin in combination with lifestyle intervention, lost on average, twice the amount of weight as compared to a control group on lifestyle intervention alone.
Yes, you may. The mechanisms of action are different for AntaGolin compared to thyroid medication (example Eltroxin), so the risk for possible drug interactions should be minimal with this combination. Literature shows that individuals suffering from an underactive thyroid may also struggle with weight management, which makes AntaGolin an ideal add-on solution.
Yes, AntaGolin may assist with appetite control. Our experience has shown that individuals suffering from insulin resistance also often suffer from an increased appetite. AntaGolin combats insulin resistance, stabilises blood sugar and insulin levels and thereby may assist with appetite control.
During the active weight loss phase, we recommend 1 AntaGolin tablet 3 times a day with meals. As soon as the waist circumference of a female measure below 80 cm, and that of a male below 94 cm, and goal weight has been reached, it is a sign that the insulin resistance has been effectively managed. At this point the dosage can be decreased to the maintenance dose of 1 tablet 2 times per day with meals along with a healthy lifestyle.
Yes, AntaGolin has a Nappi code, which means that the medical aid will pay for it provided that you have a medical aid savings option with available savings.
Diabetes is a metabolic disorder that manifests in high blood glucose levels. The underlying mechanism that leads to the development of type 2 diabetes is referred to as ‘insulin resistance’. Globally, 285 million people are diagnosed as diabetic and this number is expected to increase to 439 million by 2030. By combatting insulin resistance with AntaGolin and a healthy lifestyle, type 2 diabetes may be prevented.
The safety of using AntaGolin during pregnancy or breastfeeding has not been established. MNI therefore recommends discontinuing use of AntaGolin during pregnancy and breastfeeding. In the case where you feel the benefits of taking AntaGolin outweighs the risks, take the package insert to your consulting specialist and obtain consent and approval from your treating specialist for continued use.
Yes, you can. AntaGolin is not contraindicated in irritable bowel syndrome. Irritable bowel syndrome (IBS, or spastic colon) is a symptom-based diagnosis characterised by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits. The exact cause is not yet established, but it is believed that the correct diet may alleviate some of the symptoms. Our experience has shown that clients with IBS do very well on the MNI Cape Meal Plan in combination with FlamLeve.
Yes, we do have a free self-assessment survey available. Contrary to popular belief, it’s actually quite difficult to lose weight. Use our Assessment Survey to help you obtain more insight and gain a fresh perspective of your condition, as well as identify possible solutions and find out what others are experiencing when faced with similar problems.
Yes, you can. The mechanisms of action are different for AntaGolin compared to blood pressure medication, so the risk for possible drug interactions should be minimal. The Berberine in AntaGolin may however, in high dosages, contribute towards a lowering in blood pressure, so blood pressure should be monitored regularly. AntaGolin is contraindicated in individuals with severe low blood pressure.
Yes, you can. If you are on medicines such as warfarin to prevent blood clots, AntaGolin may however increase bleeding potential and regular blood monitoring is therefore recommended.
AntaGolin contains a blend of plant-derived phytochemical ingredients that combats insulin resistance and optimises blood-sugar metabolism. This unique combination supports multiple pathways involved in the input, output and processing of sugars in the body and the optimal regulation of metabolism.
Poorly managed blood sugar metabolism can be associated with insulin resistance, a condition that makes it difficult to lose weight. If Insulin resistance is not identified and managed appropriately it can lead to numerous conditions.
These include:
AntaGolin contains a unique blend of plant-derived phytochemical ingredients that work via multiple pathways that support blood sugar metabolism and combat insulin resistance, helping you lose weight more effectively.
AntaGolin can assist with:
AntaGolin contains a unique blend of plant-derived (phytochemical) compounds that have all been scientifically documented to help regulate blood sugar and insulin levels. These ingredients work together to slow the absorption of glucose from food, as well as support and optimise the body’s response to increased blood sugar. These are Barberry root extract, Banaba leaf extract, Apple bark extract and inositol.
Barberry root extract contains berberine, a botanical alkaloid present in a number of plants which have been used in traditional Chinese medicine for a number of conditions, including obesity and diabetes. Berberine is one of the most heavily researched plant-based compounds available, and has demonstrated the ability to slow carbohydrate digestion and absorption, improve insulin signalling, suppress fat formation and enhance energy metabolism.
Banaba leaf extract is prized in some Eastern medicine systems for its ability to alter blood sugar levels. The tree is native to India, China and the Philippines, and is valued for its violet floral displays. Its ability to reduce blood sugar, inflammation and carbohydrate absorption as well as improve insulin signaling has been proven scientifically.
Apple bark extract (Phlorodene)
Phlorodene is a proprietary formulation prepared from the bark of apple trees (Malus domestica). Besides their nutritional benefits as fruit, several substances extracted from the bark, leaves, and roots of the apple tree are also recognized for their unique medicinal qualities. Phlorizin, a phytochemical belonging to the class of polyphenols, was isolated from the bark of apple trees in 1835 and is the first known inhibitor of SGLT-2 (sodium-glucose linked co-transporter-2).
SGLT-2 is a protein that assists with glucose transport and is responsible for the reabsorption of 80-90% of the glucose filtered by the kidney. As a class of medications, the SGLT-2 inhibitors impede this process and helps block the reabsorption of glucose in the kidney. The net metabolic effect is to help lower blood sugar which assists with bodyweight reduction and optimised blood sugar control.
Traditionally, phlorizin rich apple bark has been used as an adjunct to diet and exercise to improve glycaemic control in adult patients with type 2 diabetes. It has also been reported to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease. As a polyphenol, phlorizin also exerts cardiovascular benefits in preventing heart failure through a mechanism independent of its blood glucose-lowering effects.
Inositol is a plant-based compound similar in structure to glucose. It is present in a wide variety of foods, including beans and nuts, and is naturally synthesised in the body. Scientific research has shown it is able to block glucose absorption from the diet, as well as aid in insulin signalling.
One tablet contains:
| Ingredients | |
|---|---|
| Insul-X2 Contains: Barberry root extract 60% Additives are: Chromium | 65mg 14mcg |
| Apple bark extract | 10mg |
| Banaba leaf | 750mg |
| Inositol | 80mg |
Free from: Sucrose, Lactose, Gluten and Tartrazine.
AntaGolin can be used by anyone who is battling with excess body fat, battling to gain control of their weight or may be suffering from a degree of insulin resistance. Because of its blood sugar regulation ability, AntaGolin is ideal for pre-diabetic and type 2 diabetic subjects, especially over the long term. AntaGolin can also be used by woman suffering from Polycystic Ovary Syndrome (PCOS).
Adults: Starting Dose:
Take 1 AntaGolin three times a day, with meals.
Maintenance Dose:
Take 1 AntaGolin twice a day with meals
AntaGolin should not be used if you:
AntaGolin generally has a low side-effect profile even when used for extended periods. Gastrointestinal side effects, including abdominal fullness and nausea have been reported. Individuals on diabetic medication may develop low blood sugar, especially if AntaGolin is taken on an empty stomach. It is therefore recommended that AntaGolin is taken with meals.
Yes, AntaGolin may be taken with most prescription drugs, including diabetic drugs such as metformin. Caution, however, must be taken with all classes of oral anti-diabetic medication, as the blood sugar-lowering effect of AntaGolin may enhance their action and leave you with symptoms of low blood sugar. If you are on anti-diabetic medication, consult with your doctor about whether AntaGolin is right for you. Caution must also be taken when used with warfarin.
AntaGolin contains a blend of plant-derived phytochemicals that combats insulin resistance and optimises blood-sugar metabolism. This unique combination supports multiple pathways involved in the input, output and processing of sugars in the body and the optimal regulation of metabolism.
Barberry root extract (Insul-X2):
Insul-X2 is a proprietary formulation prepared from the root of the Barberry plant, Berberis vulgaris, a flowering shrub native to Europe, Asia and northwest Africa. It is widely cultivated for its edible fruits and grown as a protective hedge on farms. Its main constituent is the botanical alkaloid berberine, found in high concentrations in the bark and roots of the plant. Berberine-based plant extracts have extensively been used in Chinese traditional medicine. Some of the therapeutic applications include the treatment of diabetes especially and obesity.
As an alkaloid, berberine is structurally based on a tetra-hydroisoquinoline scaffold, a framework now recognised as a highly versatile biochemical configuration able to bind with many biological receptors. Experiments using several biological cell models primed for insulin resistance have demonstrated berberine’s ability to up-regulate insulin receptor (InsR) expression, enhance β-cell function in the pancreas and improve the insulin signalling cascade mechanism in general.
Banabá Leaf Extract:
Banabá (Lagerstroemia speciosa) is a flowering tree that naturally occurs in China, Japan and the Indian Subcontinent. Leaves of the banabá tree are therapeutically used in Eastern traditional medicine as tea in Japan, Taiwan, and the Philippines to reduce elevated blood sugar levels.
Of particular interest to science is the role that the pentacyclic triterpenoids (PTs), a class of terpenes contained within Banabá leaf extract (BLE), play in the regulation of various signalling pathways involved in disease pathology. Research into the role of PTs concerning insulin resistance has indicated that these molecules exert their glucose-lowering effect through a multi-target, multi-pathway mechanism involving carbohydrate digestion, insulin signalling and modulation of energy metabolism.
The initial effects of Banabá leaf extract in sugar control take place in the intestines, where it slows carbohydrate digestion and absorption. This is related to the inhibiting effects that specific PTs have on the digestive enzymes responsible for the digestion of various sugars and starch, namely α-glucosidase and α-amylase, which delays gastric emptying by increasing the amount of undigested carbohydrate in the ileum and assists with appetite control and satiety.
Apple bark extract (Phlorodene):
Phlorodene is a proprietary formulation prepared from the bark of apple trees (Malus domestica). Besides their nutritional benefits as fruit, several substances extracted from the bark, leaves, and roots of the apple tree are also recognised for their unique medicinal qualities. Phlorizin, a phytochemical belonging to the class of polyphenols, was isolated from the bark of apple trees in 1835 and is the first known inhibitor of SGLT-2 (sodium-glucose linked co-transporter-2).
SGLT-2 is a protein that assists with glucose transport and is responsible for the reabsorption of 80-90% of the glucose filtered by the kidney. As a class of medications, the SGLT-2 inhibitors impede
this process and helps block the reabsorption of glucose in the kidney. The net metabolic effect is to help lower blood sugar which assists with bodyweight reduction and optimised blood sugar control.
Traditionally, phlorizin rich apple bark has been used as an adjunct to diet and exercise to improve glycaemic control in adult patients with type 2 diabetes. It has also been reported to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease. As a polyphenol, phlorizin also exerts cardiovascular benefits in preventing heart failure through a mechanism independent of its blood glucose-lowering effects.
Inositol:
Inositol is a natural biochemical compound naturally present in certain foods such as cantaloupes, oranges, beans and certain nuts. Inositol plays an essential role as the structural foundation for many signalling molecules involved in the metabolic and hormonal pathways involved in insulin’s optimal function. This includes the chain of biochemical events after insulin has bound to the insulin receptor on the outer cell membrane called insulin signal transduction and the subsequent transfer of chemical messages within cells.
Many disorders resulting from impaired insulin signalling are associated with inositol deficiency or abnormal inositol metabolic phenotypes. These abnormalities affect β-cell function in the pancreas and may further contribute to insulin resistance through decreased expression of the insulin receptor (InsR) and disruption of the insulin signalling pathway.
Correcting these deficiencies and restoring metabolic abnormalities associated with insulin resistance, inositol supplementation is beneficial to the treatment of a number of insulin-related pathologies such as polycystic ovary syndrome (PCOS), gestational diabetes, type II diabetes and metabolic syndrome (MetS).
Chromium:
Chromium is an essential trace element that plays a biochemical role in insulin action and subsequent carbohydrate, lipid and protein metabolism.
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