Insulin is natural hormone which plays a major role in regulating your use of energy. Its primary role is as a signal which tells cells what to do with glucose, a form of sugar and the main fuel substance in your body. When you eat, your food is broken down into micronutrients, amino acids and glucose. After a meal, the amount of glucose in your blood stream rises, which leads to insulin production by an organ called the pancreas. Upon receiving this signal, body parts such as your liver, fat cells and muscles begin to absorb the excess glucose and use it as energy. They do this through receptors on their cell surface, which bind to insulin and promptly activate a cascade of events that change the metabolism of the affected cells. As a result, blood glucose levels remain stable, allowing your body’s energy equilibrium to stay in place.

If you do not use much energy, eat too much, or have a diet based around energy rich food stuffs, such as fats and simple carbohydrates, it is more difficult for your body to use all the glucose as energy. Your blood glucose therefore rises rapidly after a meal. This causes your pancreas to increase the amount of insulin produced. As this continues, your cells start to become resistant to insulin, forcing your pancreas to produce even more. If this carries on, your cells continue to become resistant, and eventually your pancreas cannot produce enough insulin to keep glucose levels stable. Blood sugar then begins to rise above what can be considered normal. At first this happens in the early morning (which is why fasting glucose is measured), and then progresses to become too high after every meal (impaired glucose tolerance). At the last stage of insulin resistance, your glucose levels become raised throughout the day, leading to type 2 diabetes.

Because insulin controls how the body stores excess glucose, it also controls how the body creates adipose tissue (fat). In an insulin resistant state, your body is programmed to convert glucose to abdominal adipose tissue and to ensure the body does not use fat for energy. Insulin resistance therefore increases your weight, and weight gain makes you more insulin resistant. Insulin resistance can be reversed, and this is why early intervention and treatment is paramount.

In order to treat insulin resistance, lifestyle changes are necessary, and a healthier lifestyle should be adopted. There are also a number of medications and supplements which can help restore insulin sensitivity. MNI seeks to address insulin resistance on both fronts, through our insulin friendly, scientifically formulated Insulin-friendly (C.A.P.E.) meal plan, and through AntaGolin. AntaGolin is formulated to combat insulin resistance through a unique combination of plant based ingredients, which have been shown by research to improve insulin sensitivity and control blood glucose levels. Use AntaGolin to improve insulin sensitivity and to assist in maintaining normal blood glucose levels.

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